Associated Structures
Accession: P03395 UniProtKB/Swiss-Prot Entry
UniProtKB/Swiss-Prot PTM Description
Specific enzymatic cleavages in vivo yield mature proteins. Envelope glycoproteins are synthesized as a inactive precursor that is N-glycosylated and processed likely by host cell furin or by a furin-like protease in the Golgi to yield the mature SU and TM proteins. The cleavage site between SU and TM requires the minimal sequence [KR]-X-[KR]-R
Glycosylation Sites
Position | Structures | Description | Evidence |
---|---|---|---|
ASN-12, ASN-168, ASN-266, THR-268, SER-273, SER-275, THR-277, THR-279, ASN-302, ASN-334, ASN-341, ASN-374, ASN-410 | Associated Structures: 52 | global | GlycoSuite |
Site-Specific Information
A number of glycan structures have been assigned to specific glycosylation sites
Position | Structures | Description | Evidence |
---|---|---|---|
ASN-334 AND/OR ASN-341 | Associated Structures: 3 | Site specific | GlycoSuite |
ASN-12 | Associated Structures: 8 | Site specific | GlycoSuite |
ASN-168 | Associated Structures: 1 | Site specific | GlycoSuite |
ASN-302 | Associated Structures: 8 | Site specific | GlycoSuite |
ASN-410 | Associated Structures: 1 | Site specific | GlycoSuite |
THR-268, SER-273, SER-275, THR-277, THR-279 AND THR-304 AND/OR THR-309 | Associated Structures: 2 | Site specific | GlycoSuite |
ASN-12 AND ASN-334 AND/OR ASN-341 | Associated Structures: 4 | Site specific | GlycoSuite |
ASN-168, ASN-334 AND/OR ASN-341 AND ASN-410 | Associated Structures: 1 | Site specific | GlycoSuite |
ASN-266, ASN-302, ASN-334 AND/OR ASN-341, ASN-374 AND ASN-410 | Associated Structures: 24 | Site specific | GlycoSuite |
Notes
Accompanying information sourced from GlycoSuiteDB
- ASN-12, ASN-168, ASN-266, THR-268, SER-273, SER-275, THR-277, THR-279, ASN-302, THR-304 &/OR THR-309, ASN-334, ASN-341, ASN-374 & ASN-410 [GEYER ET AL. (1990) EUR. J. BIOCHEM. 187:95-110
Sequence
AAPGSSPHQVYNITWEVTNGDRETVWAISGNHPLWTWWPVLTPDLCMLALHGPPHWGLEYQAPYSSPPGPPCCSGSGGSSPGCSRDCNEPLTSLTPRCNTAWNRLKLDQVTHKSSEGFYVCPGSHRPREAKSCGGPDSFYCASWGCETTGRAYWKPSSSWDYITVDNNLTTNQAVQVCKDNKWCNPLAIQFTNAGRQVTSWITGHYWGLRLYVSGQDPGLTFGIRLKYQNLGPRVPIGPNPVLADQLSFPLPNPLPKPAKSPPVSNSTPTMISPSPTPTQPPPAGTGDRLLNLVQGAYQALNLTNPDKTQECWLCLVSGPPYYEGVAVLGTYSNHTSAPTNCSVASQHKLTLSEVTGRGLCIGTVPKTHQALCNTTLKTNKGSYYLVAPAGTTWACNTGLTPCLSATVLNRTTDYCVLVELWPRVTYHPPSYVYSQFEKSYRHKR