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Signal Representation and Processing of Nucleotide Sequences Host Publication: Finds and Results from the Swedish Cyprus Expedition: A Gender Perspective at the Medelhavsmuseet Authors: P. Cristea, R. Tuduce, I. Nastac, J. Cornelis, R. Deklerck and M. Andrei Publisher: IEEE Publication Date: Oct. 2007 Number of Pages: 4 ISBN: 978-1-4244-1509-0
Abstract: Sets of related signals can be represented by separating their joint variation and showing the individual signal offsets with respect to this reference. An example is the genomic signal analysis of pathogen variability. The conversion of symbolic nucleotide sequences to genomic signals allows to use signal processing methods to analyze genomic data. This approach reveals striking regularities in the distribution of nucleotides and pair of nucleotides along the sequences, in both prokaryotes and eukaryotes. Genomic signals can also be used for sequence prediction, similarly to time series prediction. The methodology is also adequate for studying the development of pathogen multiple resistance to drugs.
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